A prospective randomised study of two vaginal preparations on vaginal atrophy, sexual function and well being in post menopausal women. Women were assigned in a 2:1 ratio to ESTring and Vagifem and followed for 12 months.
Objectives of study:
The major aims of the study were to compare the safety of a continuous low-dose estradiol-releasing vaginal ring (ESTring) to that of a vaginal estradiol tablet (Vagifem) on the endometrium and the relief of subjective symptoms and signs of urogenital estrogen deficiency. Quality of life and acceptability of treatment delivery were also assessed.
Research status:
Published articles:
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